Follicular lymphoma with PAS-positive amorphous material: report of two cases.

نویسندگان

  • James Harris
  • Daniel Cherry
  • John Lazarchick
چکیده

Extracellular, PAS-positive material has been described in various lymphoproliferative disorders, but is rare in malignant lymphomas. We report two such cases of grade 2 follicular lymphoma that were investigated by routine H&E histology, immunohistochemistry, flow cytometry, and molecular pathology. Ancillary studies confirmed the monoclonality in each case and the antigenic similarity to the neoplastic cells, with the exception of bcL-2. One possible pathogenic mechanism for this extracellular material may be the exocytosis of overproduced cell membranes.

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عنوان ژورنال:
  • Annals of clinical and laboratory science

دوره 32 3  شماره 

صفحات  -

تاریخ انتشار 2002